The use of pancuronium bromide in patients receiving lithium carbonate

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Myocardial stimulation by pancuronium bromide.

The effect of pancuronium bromide on the canine myocardium was studied by observing several indices of myocardial contractility during i.v. and intracoronary infusion of the drug in an anaesthetized, open-chested dog preparation. Pancuronium produced tachycardia when given for 2 min by i.v. and intracoronary infusion with the heart intact. Following denervation and pacing of the heart the intra...

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Comparative potency of pipecuronium bromide and pancuronium bromide.

Cumulative dose-response curves were constructed to determine the comparative potency of pipecuronium and pancuronium. From these, the ED50 and ED95 values were calculated. These were 24.96 micrograms kg-1 and 44.96 micrograms kg-1, respectively, for pipecuronium and 30.42 micrograms kg-1 and 61.12 micrograms kg-1, respectively, for pancuronium.

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Fatal hyperpyrexia following the use of pancuronium bromide in the pig.

Atropine (0.04 mg/kg) was given half an hour before the operation by intramuscular injection. Anaesthesia was induced using 10 per cent halothane in an oxygen and nitrous oxide mixture (4 l./min of each) via a Magill circuit, using a Hall dog mask. After intubation, pancuronium bromide (0.13 mg/kg) was given by intravenous injection and anaesthesia was maintained with a mechanical ventilator us...

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Lithium carbonate in patients with small cell lung cancer receiving combination chemotherapy.

Lithium administration has been shown to attenuate the leukopenia associated with systemic chemotherapy. The results of a randomized trial of lithium in 45 patients with small cell lung cancer who received combination chemotherapy and radiation therapy are reported. Patients randomized to receive lithium were started on 300 mg three times daily for 18 days of every 21 day chemotherapy cycle. Pa...

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The use of lithium carbonate in the preparation for definitive therapy in hyperthyroid patients.

OBJECTIVE The aim of this study was to elucidate the effectiveness of lithium carbonate prior to thyroidectomy or radioiodide therapy in patients with thyrotoxicosis. SUBJECTS AND METHODS Lithium carbonate was used as preoperative preparation or radioiodide therapy in 5 patients with Graves' disease and in 1 patient with toxic multinodular goiter because of side effects of thionamide in 5 pat...

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ژورنال

عنوان ژورنال: Canadian Anaesthetists’ Society Journal

سال: 1974

ISSN: 0008-2856,1496-8975

DOI: 10.1007/bf03004581